Antihistamines may be first generation (sedating) or second generation (nonsedating). These two types may lead to different reactions if a person takes too much. Second generation antihistamines ...

There are two main types of antihistamines—first-generation and second-generation. First-generation antihistamines, such as chlorphenamine or promethazine, are short-acting. Side effects include ...

Remibrutinib results in significant improvement in patients still symptomatic after second-generation H1-antihistamine treatment.

Two phase 3 trials (REMIX-1 and REMIX-2) of remibrutinib in patients with chronic spontaneous urticaria who continued to have symptoms despite receiving second-generation H 1-antihistamines were ...

In this randomized controlled trial, among patients with chronic spontaneous urticaria who continue to have symptoms while on ...

Medically reviewed by Corinne Savides Happel, MD If you're pregnant, you may wonder if it's safe to use antihistamines. An estimated 10% to 15% of pregnant people do use these drugs to treat allergic ...

While second-generation antihistamines serve as the primary treatment, many patients require additional therapies, such as biologics, when symptoms remain uncontrolled. 1,2 Despite advances in ...

Phase III REMIX-1 and REMIX-2 trials demonstrated that remibrutinib, an oral BTK inhibitor, significantly reduced chronic ...