Researchers at the University of California San Diego have completed a massive genetic study that identifies key biological ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

For weeks, Steele, an assistant professor of psychiatry at the Yale School of Medicine, and members of his lab have traveled to an addiction treatment center in Middletown, Connecticut, where they are ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

Researchers at the University of California San Diego have completed a massive genetic study that identifies key biological drivers of cocaine addiction, uncovering a potential new target for ...

Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the thalamus (PVT) ...

Ramirez is an associate professor of psychological and brain sciences at Boston University. When philosophers imagined the ship of Theseus, they asked: Can a vessel that has all its planks replaced ...