Cells have evolved various DNA repair mechanisms to correct such mutations. One such mechanism is base excision repair (BER), where the mutated adenine is recognized and removed by DNA glycosylases, ...

DNA is often seen as the blueprint of life—carrying the code to govern the development and traits of an organism—but “there ...

Now, researchers at Harvard University have designed a new class of adenine base editors (ABEs ... Traditional CRISPR-Cas9 genome editing makes a double-stranded break in DNA in order to introduce ...

Combinations of these atoms form the sugar-phosphate backbone of the DNA -- the sides of the ladder, in other words. Other combinations of the atoms form the four bases: thymine (T), adenine (A ...

The DNA molecule is made up of four bases -- adenine (A), cytosine (C), guanine (G), and thymine (T). Each rung of the DNA ladder consists of two bases. In the DNA molecule, A always pairs up with ...

This process is called elongation. Three of the four nitrogenous bases that make up RNA — adenine (A), cytosine (C), and guanine (G) — are also found in DNA. In RNA, however, a base called ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

New precision genome editing technologies are transforming the therapeutic landscape for patients with certain cancers and ...

DNA is composed of building blocks called nucleotides, each of which carries one of the following bases: adenine, guanine, thymine or cytosine. These bases are the individual letters that make up ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?