“Mice are a good model for human obesity . . . but it seems to me that, for diet, the mouse literature has gone off track,” said Craig Warden, who studies the genetics of body fat accumulation at the ...

In high-fat-diet mice, this behavior broke down. Even when researchers used optogenetics to stimulate the NAc→VTA pathway with light, these mice didn’t show an increased desire to eat calorie ...

Obesity and related metabolic disorders, such as hyperlipidemia and non-alcoholic fatty liver disease, have become ...

He fed the mice a high-fat, high-sugar diet for six weeks. All had a 27% increase in body fat. He then put the mice on a restricted-calorie diet, and gave calcium to two groups of them.

Researchers explore the role of a high-fat diet in promoting the formation of premetastatic niches and platelet activation.

The research focused on the effects of KLX on human umbilical vein endothelial cells (HUVECs) subjected to TGFβ1-induced EndMT and on atherosclerotic lesions in ApoE-/- mice fed a high-fat diet.

SO FOR ME, WHEN I STARTED STUDYING OBESITY, I WAS EXPECTING IN MICE. WHEN YOU PUT THEM ON HIGH FAT DIET THAT WE’RE GOING TO SEE SOME KIND OF LIKE FOOD ADDICTION, THEY’RE GOING TO BE SO EAGER ...

"But our study shows that the reality is more nuanced. What we found is that in mice exposed to a chronic high-fat diet, the brain's reward response -- particularly in circuits involving dopamine ...