a transcription factor necessary for the transient expansion of B cells preceding plasma cell differentiation, via coupling its translation to its decay.

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor ...

Recently, Quantitative Biology published an article entitled “Single-cell analyses reveal impaired type B spermatogonia differentiation and meiotic entry in C-Nap1-null testes”, which uses ...

Project 4: The goal of this project is to investigate how differentiation and function of B cells are impaired during lung cancer progression. We will investigate the impact of myeloid-lineage cells ...

ARV-393 is Arvinas’ investigational PROteolysis TArgeting Chimera (PROTAC) degrader targeting the B-cell lymphoma 6 protein (BCL6), a transcriptional repressor and major driver of B-cell lymphomas.

In this study, the impact of C-Nap1 on spermatogenesis using C-Nap1 knockout mouse models was investigated. Single-cell RNA ...