Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

Conventionally, the first and second stimulation signals in vitro, simulating the process in vivo ... signals to induce T cell proliferation, separate from CD28 molecule signaling. Our other products ...

T cells, move over. B cells are now reported ... the mannan-binding lectin and alternative pathways of complement activation. The classical and alternative pathways of complement activation ...

The aberrant activation of B cells plays a central role in the pathogenesis of various autoimmune diseases and B-cell lymphomas. Now, Honigberg and colleagues describe an orally available ...

This process, known as T-cell priming, begins when T cells encounter dendritic cells (DCs) in the lymph nodes. These cells present antigens – fragments of pathogens – to the T cells and activate them ...