In the study, "Disease diagnostics using machine learning of B cell and T cell receptor sequences," published in Science, researchers analyzed BCR heavy chain and TCR beta chain sequences from 593 ...

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine ...

BCR-ABL1 is an abnormal gene present in certain types of leukemia. Genetic testing for BCR-ABL1 helps doctors diagnose these cancers and assess their response to treatment. If you or someone you ...

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine ...

BCR-ABL forms a dimer and/or tetramer through the coiled-coil domain in the N terminus of BCR, which is thought to promote BCR-ABL activation and oncogenesis by facilitating transphosphorylation ...