higher-order structures obtained through complementary base-pair folding. From the RNA Tie Club to today, the more scientists have studied RNA, the more surprises they have uncovered. New ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

All five nucleobases that make up DNA and RNA have now been detected in meteorite samples ... as terrestrial soil and other environments also contain nucleotide bases. “I think [the researchers] ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

ADAR1 converts adenosine to inosine in double-stranded RNA, a process essential for preventing unwarranted immune responses, yet the molecular basis of this editing had remained unclear.

RNA-based therapeutics are gaining traction due to advancements in delivery technologies, despite historical challenges with ...

RNA-based therapies, such as small interfering RNA (siRNA) and antisense oligonucleotide (ASOs), rely on the specific base-pairing properties of uracil to target and regulate disease-related genes. In ...

The research work forms the potential basis for more complex RNA machinery. One major challenge in constructing synthetic cells is manufacturing proteins, which are responsible for nearly all ...