Sep 21, 2025; Santa Clara, California, USA; Arizona Cardinals tight end Trey McBride (85) runs after the catch against the San Francisco 49ers during the second half at Levi's Stadium. Mandatory ...

TV: Fox. Radio: 98.7. Last time they played: The Cardinals were 2-0 when they arrived at Levi’s Stadium in September, and they nearly stretched their undefeated start to three games. Late in the ...

Discover the key strategies the 49ers must execute to beat the Cardinals in Week 11 as San Francisco fights to stay alive in the NFC playoff race.

The Arizona Cardinals had their top running back questionable entering Sunday's tilt against the San Francisco 49ers.

San Francisco 49ers kicker Eddy Piñeiro and linebacker Tatum Bethune have been standouts as in-season substitutes, but both will miss several games after injuries sustained against the Cardinals.

SANTA CLARA, Calif. (AP) — Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly two years. While Purdy looked sharp in the 41-22 victory over the Arizona ...