Shanghai's RiboX Therapeutics begins first-ever circular RNA clinical trial, targeting dry mouth in cancer patients. Company ...

Circular RNAs often form as the pre-mRNA molecule is processed into its final transcript via splicing, in which introns are removed and exons are linked together. Most circular RNAs are thought to be ...

Circio and Entos have initiated a research collaboration that will involve joint development and in vivo delivery testing of ...

Recent research has revealed many surprises about circular RNAs, from findings that they are translated in vivo to links between their expression and disease. Circular RNA biogenesis occurs when RNA ...

Lipid nanoparticle (LNP) mRNA vaccines emerged during the COVID-19 pandemic to form an almost miraculous protection against a virus, which killed millions around the world. Aided by expedited ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to ...