A candidate-gene study of Chinese Han children finds nominal links between complement-related gene variants and severe ...

The complement system in teleost fish constitutes a cornerstone of innate defence, integrating classical, lectin and alternative activation routes to eliminate pathogens and shape inflammatory ...

Allergic asthma is driven by a complex interplay between innate and adaptive immunity in which the complement system plays a central role. Activation of complement via the classical, lectin or ...

December 4, 2024 – Jérémie Le Pen wants to understand the workings of the “innate immune system”—the part of the human immune system that puts up an immediate defense when it encounters a pathogen.

One of the most frustrating patterns in modern cancer treatment is that a therapy which works brilliantly at first can ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

Researchers at the Francis Crick Institute, King's College London and Complutense University of Madrid have shown that γδ T ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...