Chemists have come to a deeper understanding of how photosynthetic bacteria convert light into chemical energy and discovered why one step in the process may be more robust than previously realized, ...

The Macromolecular X-ray Crystallography Core and the Recombinant Protein Production and Characterization Core have merged into a new core, the “Recombinant Protein Production, Characterization, and ...

Neutron crystallography is an important complementary technique to X-ray crystallography since it provides details of the hydrogen atom and proton positions in biological molecules. Furthermore, as ...

One longstanding problem has sidelined life-saving drugs, stalled next-generation batteries, and kept archaeologists from identifying the origins of ancient artifacts. For more than 100 years, ...

Drug development relies on having an accurate knowledge of the structure of organic molecules such as proteins, nucleic acids, and viruses. The field is a multi-billion-dollar industry, and the need ...

Scientists at the Department of Energy’s Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B 6-dependent protein, potentially opening avenues for new antibiotics ...

Chemists have come to a deeper understanding of how photosynthetic bacteria convert light into chemical energy and discovered why one step in the process may be more robust than previously realized, ...

The modular nature of antibodies allows the design of antibody-related formats with tailored characteristics. The antibody’s Fc part, encompassing the effector functions, represents an attractive ...

A new study has captured atomic-resolution snapshots of a brown recluse spider toxin latched onto cell-membrane lipids, revealing exactly how the enzyme shears off molecular headgroups and reshapes ...

Knowledge of H-bonding networks, water molecule orientations and protonation states, along with details of hydrophobic and electrostatic interactions, can prove vital towards a better understanding of ...