To uncover the sites of protein-DNA interactions at genome scale, Bing Ren, a former postdoctoral researcher in Young’s lab and now a gene regulation researcher at the University of California, San ...

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered ...

"DNA is literally cut out of one bacterium's genome and transferred over to another with the help of RdfS protein," Dr. Verdonk ... of the coiled–coil interactions in human SFPQ, Nucleic Acids ...

revealing that the fork protection occurs through dynamic protein–DNA interactions. "Although the single ring structure had been observed previously, this is the first structure showing the two ...

The team initially set out to study another replication machinery protein, single-stranded DNA-binding protein, and its interaction with DNA polymerase. However, they first needed to establish how the ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

They focused on a protein called JUN, which plays a key role in DNA binding and cellular communication ... the impact of each mutation on JUN's interactions with 54 different partner proteins.

a deep-learning-based method to detect these types of footprints of DNA-protein interactions. Using data from 170 human liver samples, the researchers observed 809 "footprint quantitative trait ...

a deep-learning-based method to detect these types of footprints of DNA-protein interactions. Using data from 170 human liver samples, the researchers observed 809 "footprint quantitative trait ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair ... through competitive binding and cooperative interactions. Specifically, ZNF451 and RNF8 mutually inhibit ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair, ...