For cancer cells to spread, a group of cells must work together to invade new tissues. This process is called Epithelial-Mesenchymal Transition (EMT). During EMT, cancer cells change and become ...

In fact, only 12% of pancreatic cancer patients survive five years after diagnosis. One key feature of metastasis, Dr. Brekken explained, is epithelial-to-mesenchymal transition (EMT), in which ...

Researchers at Karolinska Institutet, led by Dr. Helin Norberg and Dr. Erik Norberg, have identified a previously unknown ...

is frequently re-activated in metastatic and recurrent tumors. Our work provided a conceptual understanding depicting a causal role for RNA alternative splicing in EMT and breast cancer recurrence. We ...

Cancer stem cells (CSCs), the sub-population of tumour cells that possess tumour-initiating potential, can adopt phenotypes that drive tumour invasion and metastasis and express heightened resistance ...