Gastrulation is a process common to nearly all metazoan organisms during which an embryo with distinct tissue layers develops out of a seemingly unstructured assembly of cells referred to as 'blastula ...

Molecular and cellular mechanisms of epithelial–mesenchymal transition (EMT), crucial in development and pathogenesis, are still poorly understood. Here we provide evidence that distinct cellular ...

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as gastrulation, ...

Gastrulation is the process that creates the 3 axes of the body. While this stage was thought to be driven solely by chemical signals, new tools made it possible to test whether physical forces play ...

Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

How does the “body” take shape? The body of animals is highly complex, containing distinct regions that carry out specific functions. As the body forms during embryogenesis, three germ layers are ...

The mechanisms used by embryos to pattern tissues across their axes has fascinated developmental biologists since the founding of embryology. Here, using single-cell technology, we interrogate complex ...

Researchers offer a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, and discuss the implications ...

Jusque-là sphérique, l'embryon s'invagine pour former une nouvelle cavité interne (en plus du blastocèle préexistant) : l'archentéron, futur tube digestif. À la fin de cette étape, la gastrula adopte ...

When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...

Gastrulation is the formation of the three principal germ layers - endoderm, mesoderm and ectoderm. Understanding the formation of the basic body plan is not only important to reveal how the ...

Scientists from Helmholtz Zentrum München revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has ...