New findings show that removing Centaurin-α1, a protein elevated in Alzheimer’s disease, significantly reduces inflammation, plaque buildup, and cognitive deficits in a well-established mouse model.

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial ...

Though almost every cell in your body contains a copy of each of your genes, only a small fraction of these genes will be expressed, or turned on. These activations are controlled by specialized ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

New research published in the journal eNeuro examined whether eliminating a protein that is elevated in the brains of those ...

Metabolic and regulatory networks may be expanded by coupling high-throughput phenotyping and gene expression data with the predictions of a computational model. (Reprinted with permission, Nature, ...

Tracking how genes switch on and off in the brain is essential for understanding many neurological diseases, yet the tools to ...