In vitro tests have demonstrated that second-generation antihistamines have improved H 1-receptor specificity ... Investigational models like the histamine-induced skin wheal-and-flare model ...

Cysteinyl leukotrienes are established mediators of bronchial asthma and have agonist roles analogous to those of histamine in allergic ... inflammatory response via receptors on smooth muscle ...

Abstract and Introduction Predicting and Establishing the Clinical Efficacy of a Histamine H Application ... for evaluating the efficacy of the H 1-receptor antagonist desloratadine.