A man was shot at while driving on Interstate 64 in St. Louis County on Feb. 5. According to police, the man was shot at when ...

ST. LOUIS — Police are investigating a deadly wrong-way crash that happened early Friday morning on Interstate ... westbound I-64 reopened at about 6:20 a.m., according to the Missouri ...

ST. LOUIS — Authorities have identified Alexander Whalen, 29, as a driver killed in a wrong-way collision on Interstate 64 last week when a pickup truck traveling in the wrong direction struck ...

ST. LOUIS — The Missouri Department of Transportation has announced overnight closures of the Compton Avenue bridge over ...

ST. LOUIS – A man was left dead and another was left injured after a wrong-way driver caused a violent crash on Interstate 64 near downtown overnight Friday morning. The crash happened around 1: ...

Cancel anytime. ST. LOUIS — A man died early Friday after his car was hit by a wrong-way driver on Interstate 64 in St. Louis. The crash was about 1:45 a.m. on westbound I-64 near South ...

Chesterfield will soon be getting some noteworthy new tenants. The state of Missouri acquired an office off Interstate 64 and Timberlake Manor Parkway to move some employees previously based out of ...

If you use I-255 to get to Interstate 64 on the way to downtown St. Louis, you need a new route. The best alternate routes are Illinois Route 3 to the west and Route 157 to navigate around the ...