RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in ...

A micrograph showing inflammatory responses in the cortex of the new model mouse. Alzheimer's disease patients and mouse ...

with reported improvements in amyloid plaques in mouse models being an indirect by-product. "Now we know that's not the whole story," he said. "Ketone bodies interact with damaged and misfolded ...

They then used this treatment to deliver amyloid-beta antibodies into the brain of an Alzheimer’s mouse model and achieved both a reduction of amyloid plaques and also improved cognitive ...

“This model is important because it is the first in the world to demonstrate the protective effect of the Icelandic mutation against amyloid pathology in animals,” says Sasaguri. Using their new mouse ...