The adhesion of cells to the surrounding extracellular matrix and their stimulation by soluble growth factors provide the environmental cues necessary to control a cell's decision to survive, ...

Paxillin is a focal adhesion-associated, phosphotyrosine-containing protein that may play a role in several signaling pathways. Paxillin contains a number of motifs that mediate protein–protein ...

Researchers from the University of Geneva (UNIGE) in Switzerland, in collaboration with the University of Tampere in Finland, say they have highlighted the critical role of paxillin, a protein that ...

Research teams are analyzing how proteins work together to enable our cells to both stick and move. The marker protein paxillin is at the center of their interest. The tissue in our body can only hold ...

Scientists have highlighted the key role of a protein called paxillin, which enables cells to perceive their environment and anchor at the right place with the help of cellular 'crampons'. Indeed, ...

A team of international researchers led by scientists at City of Hope provides the most thorough account yet of an elusive target for cancer treatment. Published in Science Advances, the study ...

A team of international researchers led by scientists at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical ...

Focal adhesion (FA) proteins may be critical elements in the production of dystrophic neurites in Alzheimer's disease, according to research presented in the January 15 Journal of Neuroscience. Recent ...

Currently, the United States lacks FDA-approved treatments for liver fibrosis, highlighting the critical need to understand the cellular biology and pathways associated with this condition. Science X ...

A team of international researchers led by scientists at City of Hope ®, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National ...

The tissue in our body can only hold together if the cells adhere not only to each other, but also to extracellular structures, such as collagen fibers of the connective tissue and the skin. How ...