Moreover, sustained suppression of ADH4 in HCC cells disrupts retinoic acid synthesis, leading to reduced expression of the Wnt/β-catenin signaling inhibitor ... its potential as a prognostic ...

“This is another important breakthrough in understanding the Wnt pathway and the importance of Fzd4 stimulation as we look to leverage this important pathway in understanding and potentially ...

dual PARP and WNT pathway inhibitor—as a personalized cancer treatment using its proprietary, drug-specific Drug Response Predictor (DRP ®) patient selection technology today announced the ...

Pyrvinium pamoate, a medication approved by the Food and Drug Administration in 1955 to treat pinworms, has been shown to have antitumor potential ... the Wnt signaling pathway as one of the ...