Scientists are exploring targeted drugs to prevent cyst formation ... and treating the disease. These findings provide fresh insight into the genes responsible for renal function decline and ...

Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the ...

The incidence of chronic kidney disease (CKD) is rising. Uncontrolled diabetes and hypertension are two major causes for CKD.

Preliminary data suggest he’s correct. “When Fbxw7 is deleted, we found that (those) mice develop slowly progressing cystic kidney disease without kidney enlargement, tubulointerstitial ...

For patients with polycystic kidney disease (PKD), a common genetic disorder that ravages the waste-removing organ with cysts, dialysis and transplantation are among the only treatments.

Polycystic kidney disease (PKD) is a genetic disorder whereby a large number of cysts develop primarily within the kidneys, but also in other organs. PKD can be autosomal dominant (one mutated ...

Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, ...

ADPKD is caused by mutations in the PKD1 or PKD2 genes, resulting in end-stage renal disease. The disease is characterized by the development of multiple fluid-filled cysts, primarily in the kidneys.

Cysts, fibrosis, and tubular degeneration form the typical triad of pathologies leading to the gradual decline in kidney ...