Add-on oral antihistamines or montelukast (Singulair) do not add much benefit. In three separate trials, researchers randomized 3398 adolescent and adult patients with moderate-to-severe SAR ...

Treatments for SAR aim to minimise symptoms ... and comparisons analysed were those including topical or systemic antihistamines, decongestants, leukotriene antagonists and ipratropium bromide.

Objective: To compare loratadine with fexofenadine and placebo in relieving symptoms of seasonal allergic rhinitis (SAR). Design: A randomised, double-blind, double-dummy, placebo-controlled ...

Eosinophils play a crucial role in allergic responses, secreting cytokines and inflammatory mediators that exacerbate AR ...