A study maps how toxic tau disrupts synapses over time, showing early postsynaptic damage that later spreads presynaptically.
Figure 1. To observe dynamically changing synapses, dimerization-dependent fluorescent protein (ddFP) was expressed to observe flourescent signals upon synapse formation as ddFP enables fluorescence ...
Breakthroughs, discoveries, and DIY tips sent six days a week. Terms of Service and Privacy Policy. One of the brain’s most important properties is its flexibility ...
Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...
Schematic representation of axonal transport vesicles (blue) carrying presynaptic proteins (SV and AZ proteins). Kinesin motor proteins (KIF1A) attach these vesicles and carry them along the axons to ...
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