A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to ...

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing ... SCP-Nano ...

The researchers injected lung-targeted SORT LNPs intravenously to healthy mice engineered to express a red fluorescent protein in any cell that underwent gene editing. When Siegwart’s team isolated ...

ARMMs brings precision medicine through targeted, non-viral vesicular delivery. Synergy of ARMMs and eTurna™ LNP platforms means ... delivery in a variety of tissues, including retinal, lung ...

Phospholipids are key components of cell membranes, and are used in the creation of lipid nanoparticles (LNPs) for targeted drug delivery ... eliminated from liver tissue, reducing long-term ...

enables the systematic and reliable engineering of lipid nanoparticles (LNPs) for precise mRNA delivery into specific organ. Fig. 6 Surface modification strategies for tissue targeting of LNP-mRNA.

Obesity is an increasingly prevalent human condition in developed societies. Despite major progress in the understanding of the molecular mechanisms leading to obesity, no safe and effective ...

Adding ARMMs to the company's eTurna® LNP delivery platform greatly expands the reach ... The ARMM platform is biocompatible, redosable, simple to manufacture, can be targeted to specific tissues, and ...