The interplay between contractility and mechanosensing in striated muscle is important for tissue morphogenesis, load adaptation, and disease progression, but remains poorly understood. Here, we ...

DNA 5-methylcytosine (5mC) and its oxidized form, DNA 5-hydroxymethylcytosine (5hmC) are prevalent epigenetic markers that play crucial roles in regulating gene expression within the human genome 1.

Now that the researchers have shown that intercellular flow determines how tissues will adapt to physical forces, the results can be applied to understand a wide range of physiological conditions, ...