If DNA is a book, then how is it read? Learn more about the DNA transcription process, where DNA is converted to RNA, a more portable set of instructions for the cell. The process of transcription can ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

There are only about 20,000 different genes in the human genome, yet our bodies are filled with an incredible diversity of cell types performing innumerable functions. The key to that diversity in ...

The central dogma of molecular biology states that genes make RNAs, which then make proteins. Researchers in Germany have now discovered how the crucial first steps in RNA synthesis are executed -- ...

What new Howard Hughes Medical Institute president Robert Tijan said about the activities of our genes in 1995: They are tightly regulated by elaborate complexes of proteins that assemble on DNA.

The RNA polymerase enzyme is a large complex made up of multiple subunits 1. The prokaryotic form of RNA polymerase has four subunits capable of transcribing all types of RNA. In eukaryotes, these ...

Messenger RNA (mRNA) technology came of age during COVID-19 with several vaccines and therapeutics coming to market. However, since the height of the pandemic, the flow of new mRNA-based products has ...

Plasmids containing the VA RNA genes of adenovirus are faithfully transcribed by a crude cytoplasmic extract containing DNA-dependent RNA polymerase III [Wu, G.-J. (1978) Proc. Natl. Acad. Sci. USA 75 ...