Transferrin is the principal iron-binding glycoprotein in vertebrate circulation, responsible for safe transport of ferric ions and regulation of systemic iron distribution. Each molecule comprises ...

The blood brain barrier (BBB) exists to protect the brain from pathogens and other toxins but makes central nervous system (CNS) diseases hard to treat with conventional drugs. For example, many ...

Individuals with β-thalassemia develop progressive systemic iron overload, resulting in high morbidity and mortality. These complications are caused by labile plasma iron, which is taken up by ...

A new study led by researchers at the Graduate Entry Medical School (GEMS), University of Limerick (UL) has found that people with low levels and very high levels of a commonly measured laboratory ...

Over the last three decades, scientists have devised molecular shuttles that slip enzymes, antibodies, and other molecules into the central nervous system (CNS) by attaching them to the transferrin ...

For decades scientists have sought a way to sneak large drugs across the blood-brain barrier. These efforts received a boost in 2011, when researchers led by Ryan Watts at Genentech, South San ...

NEW YORK--(BUSINESS WIRE)--Apertura Gene Therapy, a biotechnology company opening opportunities in genetic medicine for treating debilitating diseases with limited options, today unveiled its ...

Low iron saturation occurs when the amount of iron in the blood decreases below the recommended range. Measuring transferrin is one way to determine iron saturation. Iron saturation refers to the ...

A total iron binding capacity (TIBC) test is a type of blood test that measures the capacity of transferrin, a carrier protein, to bind with iron. The results can help diagnose certain health ...

InVitria was recently cited in a review article titled “Recombinant human transferrin: Beyond iron binding and transport”, published in Biotechnology Advances. The article describes the importance of ...