"The transition begins when cells acquire an altered or hybrid identity, because of inflammation or damage that can potentially predispose them to a cancerous state, even without cancer-driving ...

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic “marks” in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may ...

But with base editing, we can only engineer transition mutations, such as thymine substituting for cytosine. We therefore miss roughly half the mutations seen in cancer patients. We have begun to ...

Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer ...

“The transition begins when cells acquire an altered or hybrid identity, because of inflammation or damage, that can potentially predispose them to a cancerous state, even without cancer-driving ...

The team is optimizing the cancer genome analysis system to integrate it into CRC diagnosis and tailor treatments based on ...

Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide.

"This work shows a key role for epigenetic memory in the transition to cancer even without a genetic mutation," says Feinberg. "This transition state is probably a normal way that the pancreas ...

“This work shows a key role for epigenetic memory in the transition to cancer even without a genetic mutation,” says Feinberg. "This transition state is probably a normal way that the pancreas ...