The 5′ end of newly synthesized RNAs bears a triphosphate derived from the first transcribed nucleotide. In eukaryotes, the distal phosphate is replaced by an inverted, methylated GMP to form ...

Many of the nucleoside antibiotics exhibit their activity only after conversion into their nucleotide form (mono- or triphosphate) once inside the cell. A number of nucleoside analogues which were ...

Each nucleoside triphosphate is made up of three phosphates ... the free energy needed to drive the incorporation of each nucleotide into the growing DNA chain. The reaction shown on the bottom ...

Adenine is also a component of important biomolecules such as ATP (adenosine triphosphate), which is the primary energy ... GTP is another purine nucleotide that plays a crucial role in cellular ...