Endothelial-to-Osteoblast Conversion (EC-to-OSB) regulates bone formation and homeostasis via the Kindlin-2/Piezo1/TGFβ/Runx2 axis. Reduced Kindlin-2 in endothelial ...

A newly discovered receptor switch that boosts bone growth could transform how we treat osteoporosis, by stimulating the body’s own bone-building machinery using a targeted drug and even mechanical ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

Scientists develop a new material that protects stem cells and helps repair facial bone damage by reducing harmful stress and inflammation in the body. (Nanowerk Spotlight) Maxillofacial bone defects ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

"Even low numbers of mutated cancer cells profoundly affected the blood-producing system and bone homeostasis," said senior study author Patrycja Dubielecka, an associate professor at the Warren ...

Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential ...

About 90% of patients with multiple myeloma (MM) develop severe bone disease, known as myeloma bone disease (MBD). This occurs due to the ability of MM cells to disrupt bone homeostasis, leading to ...

Bone health might not be the most glamorous topic on your wellness radar, but it deserves a spot, especially once you hit your 30s. Most women reach peak bone mass by age 35, and from there, density ...