In addition to Hatshepsut—and another younger daughter who apparently died in childhood—it’s believed that Thutmose I fathered two sons with Queen Ahmes, both of whom predeceased him.

But as his mother was only a minor wife, his marriage to Hatshepsut (also a daughter of Thutmose I, by his principal wife Ahmose) cemented his position in line to the throne. Around 500 years ...