The cytoskeleton comprises microfilaments, microtubules and intermediate filaments (IFs) 1. Vimentin is the most abundant IF protein and has a critical role in stabilizing intracellular architecture 2 ...
A recent study has found that extracellular vimentin can bind to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in vitro, and antibodies against vimentin can decrease ...
The vimentin filament network plays a key role in cell architecture and signalling, as well as in epithelial–mesenchymal transition. Vimentin C328 is targeted by various oxidative modifications, but ...
Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122 Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, ...
A recent iScience journal study reports that cell-surface vimentin functions as a co-receptor for the entry of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells to ...
Vimentin intermediate filaments are generally present in mesenchymal cells. Vimentin is found not only in eukaryotic cells, but also in bacteria, where it helps to form the cytoskeleton. Vimentin is ...
Binge drinking is known to increase the risk of developing dementia and/or brain damage. A new study used rodents to test markers of neurodegeneration to determine a threshold for brain damage. The ...
Recent evidence has enhanced the image of astrocytes, suggesting these glial cells are a source for stem cells (see ARF related news story), and that they mop up Aβ (see ARF related news story). But ...
Prognostic classifier for stage II gastric cancer based by support vector machine. Irinotecan/mitomycin C (IRI/MMC) combination as second-line chemotherapy in patients with metastaic gastric carcinoma ...
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Cytoskeletal filament formation: Scientists discover new details about vimentin filaments critical for wound healing
Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, according to a study published in the Proceedings of the National Academy of Sciences.
Vimentin intermediate filaments are generally present in mesenchymal cells. Vimentin is found not only in eukaryotic cells, but also in bacteria, where it helps to form the cytoskeleton. Vimentin is ...
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