Background Current risk scores inadequately predict long-term mortality after transcatheter aortic valve replacement (TAVR), ...

Objective Frequent flares of pericardial inflammation in recurrent or incessant pericarditis with corticosteroid dependence and colchicine resistance may represent a risk factor for constrictive ...

Objective To evaluate the association between chocolate intake and incident clinically apparent atrial fibrillation or flutter (AF). Methods The Danish Diet, Cancer, and Health Study is a large ...

Comparative evaluation of biological and mechanical prostheses for aortic valve replacement in a middle-aged population: a population-based cohort study ...

Cardiovascular disease (CVD) mortality in the UK is declining; however, CVD burden comes not only from deaths, but also from those living with the disease. This review uses national datasets with ...

Objective To examine whether elevated resting heart rate (RHR) is an independent risk factor for mortality or a mere marker of physical fitness (VO2Max). Methods This was a prospective cohort study: ...

Acute aortic syndrome and in particular aortic dissection (AAD) persists as a cause of significant morbidity and mortality despite improvements in surgical management. This clinical review aims to ...

Clinical introduction A 49-year-old man presented to the emergency department following sudden onset chest pain with collapse. He was refurbishing his home when he collapsed on the floor with chest ...

Aims of MINAP To audit the quality of care of patients with acute coronary syndrome and provide a resource for academic research. Quality of care interventions Feedback to hospitals, ambulance ...

Since the inaugural description in 1959 by Prinzmetal,1 coronary artery spasm and abnormal coronary artery vasomotion have been extensively studied both clinically and scientifically. There is no ...

Coronary disease mortality, incidence, and clinical presentation vary greatly over time. In many countries with a high prevalence of coronary heart disease, mortality is now falling rapidly. 1–4 ...