High-intensity focused ultrasound (HIFU) is an increasingly used, locally ablative therapy option in localized prostate cancer (PCa). Multiparametric MRI (mpMRI) is currently used for tumor ...

Nuclear medicine has undergone a remarkable transformation, with both diagnostic and therapeutic applications expanding at an unprecedented pace. This progress is rooted in fundamental discoveries by ...

Journal of Nuclear Medicine December 2023, jnumed.123.266741; DOI: https://doi.org/10.2967/jnumed.123.266741 ...

Gastroenteropancreatic neuroendocrine tumors are relatively rare neoplasms, characterized by a propensity to secrete hormones that cause distinct clinical syndromes. During the past decade, the ...

The deployment of artificial intelligence (AI) has the potential to make nuclear medicine and medical imaging faster, cheaper, and both more effective and more accessible. This is possible, however, ...

Journal of Nuclear Medicine December 2025, jnumed.125.270117; DOI: https://doi.org/10.2967/jnumed.125.270117 ...

Radioligands, such as 18 F-labeled florbetapir (Amyvid; Eli Lilly), selectively bind to amyloid-β (Aβ), allowing direct PET imaging of Aβ plaques in patients with Alzheimer disease (AD) (1).

Amyloid-β (Aβ) accumulation in the brain is a pathologic indicator of Alzheimer disease (AD) that can be imaged using PET. Second-generation PET radiotracers, such as [18 F]florbetaben, [18 ...

The aim of this study was to prospectively compare whole-body PET/MR imaging and PET/CT, qualitatively and quantitatively, in oncologic patients and assess the confidence and degree of inter- and ...

Journal of Nuclear Medicine November 2025, jnumed.125.270568; DOI: https://doi.org/10.2967/jnumed.125.270568 ...

The field of theranostics dates back over 80 y, when Hertz and Roberts first used radioactive iodine to treat thyroid disease. Recent theranostic approvals for neuroendocrine tumors and prostate ...

Most well-differentiated neuroendocrine tumors (NETs) express high levels of somatostatin receptors, particularly subtypes 2 and 5. Somatostatin analogs (SSAs) bind to somatostatin receptors and are ...