Xencor Announces Positive Interim Results From First-in-Human Healthy Volunteer Study of XmAb942, a High-Potency Extended Half-Life Anti-TL1A Antibody ... "Our Phase 1 data for XmAb942 validate ...

today announced positive interim results from its first-in-human study of XmAb942, a high-potency, extended half-life, investigational anti-TL1A antibody in clinical development for patients with ...

Sanofi’s blockbuster ambitions for amlitelimab hit a bump in the road this morning with the news that the highest dose of the anti-OX40-ligand monoclonal antibody missed the main goal of a phase ...

A large cohort of patients with a positive myositis antibody result (1068 individuals) were explored for relevant myositis-spectrum diagnoses. The PPV for a myositis diagnosis was highest for ...

The images were compared to the patient with Jo-1, those with TIF1, or centromere ... while these were detected in capillary scope in the literature in anti-MDA5 antibody positive patients.

Introduction: Anti-SSA antibodies target two unrelated proteins, Ro52 (E3 ligase) and Ro60 (RNA binding protein). Previous studies indicate that anti-Ro52 antibodies are frequently associated with ...

We identified 6 individuals (0.47%) presenting as double positive for anti-MDA5 and anti-ARS antibodies. Of these, 2 (33.3%) were anti-PL-12+, 2 (33.3%) were anti-Jo-1+, 1 (16.7%) was anti-EJ+, and 1 ...

For PK or ADA assays, anti-idiotype antibodies (Anti-IDs) are powerful tools to quantify the concentration of antibody drugs in patient samples and act as positive controls for anti-drug ...