Introduction: Antibody maturation in the lymphoid follicle produces antibodies with improved binding ... (BCR)-derived HLA-DR epitopes present in memory antibody repertoires from seven healthy human ...

Introduction: Chimeric antigen receptor ... T cells in our binding titration (Figure 4). Our data on the different epitopes of TSHR as the binding domain of the CAAR T cells suggests that, in ...

Indeed, it qualitatively appears that the intermediate 4-, 5-, and 6mer BOAS were the most immunogenic and this length may be sufficient to effectively engage and crosslink BCR for potent stimulation.

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of ...

B Cells are a type of lymphocyte whose primary purpose is to generate highly specific antibodies in response to a foreign antigen. The B cell receptor (BCR) signaling pathway regulates B cell ...

BCR cross-linking by the self-antigens initiates BCR editing, which rearranges the Ig light chain genes to substitute the self-reactive receptors with the non-self-reactive receptors. The B cells ...

Cite this: Abl Tyrosine Kinase Inhibitors for Overriding Bcr-Abl/T315I: From the Second to Third Generation - Medscape - Sep 01, 2008.

A novel immunoenhanced virus-like particle carrier (CR-T3) derived from the roundleaf bat HBV core antigen ... the sA epitope (HBsAg-aa119-125) and exhibit more remarkable and prolonged HBsAg ...