This study introduces a novel approach for enhancing immune responses in wild-type mice by utilizing pre-formed immune complexes, using the receptor-binding domain (RBD) of SARS-CoV-2 as a model ...

1. An isolated human antibody, or antigen-binding portion thereof, that binds to human IL-12 and dissociates from human IL-12 with a K4 of 1×10−10M or less and a koff rate constant of 1×10−3 ...

The risk stratification by EAU was proposed for patients with BCR, including the doubling time of the prostate-specific-antigen and Gleason score as predictors for survival. Although stratification ...

In silico screening identified three potential drug-binding sites and novel small-molecule modulators that reduce dye uptake in cochlear explants. KtrAB is a major potassium uptake system that has ...

Vaccine platforms carrying one or more tumor antigens are expected to stimulate specific antitumor ... as well as the combined application of immunotherapy strategies such as ICB, multi-epitope and ...