A man was shot at while driving on Interstate 64 in St. Louis County on Feb. 5. According to police, the man was shot at when ...

ST. LOUIS — Police are investigating a deadly wrong-way crash that happened early Friday morning on Interstate ... westbound I-64 reopened at about 6:20 a.m., according to the Missouri ...

ST. LOUIS — Authorities have identified Alexander Whalen, 29, as a driver killed in a wrong-way collision on Interstate 64 last week when a pickup truck traveling in the wrong direction struck ...

ST. LOUIS – A man was left dead and another was left injured after a wrong-way driver caused a violent crash on Interstate 64 near downtown overnight Friday morning. The crash happened around 1: ...

Cancel anytime. ST. LOUIS — A man died early Friday after his car was hit by a wrong-way driver on Interstate 64 in St. Louis. The crash was about 1:45 a.m. on westbound I-64 near South ...

If you use I-255 to get to Interstate 64 on the way to downtown St. Louis, you need a new route. The best alternate routes are Illinois Route 3 to the west and Route 157 to navigate around the ...