Naturally occurring dicentric chromosomes allow examination of complex cis–acting effects that regulate kinetochore function and chromosome segregation. Dicentric chromosomes with well ...

The correction of erroneous kinetochore-microtubule attachments requires tension-dependent phosphorylation of key substrates. This study reveals a novel and essential recruitment mechanism of the ...

This study presents a valuable finding that MK2 inhibitor CMPD1 can inhibit the growth, migration, and invasion of breast cancer cells both in vitro and in vivo by inducing microtubule ...

1 Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, United States 2 Howard Hughes Medical Institute, Chevy Chase, MD, United States Summary: The term “anaplasia” was coined in 1890 ...

Institute of Human Genetics, University of Cologne, 50931 Cologne, Germany Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital, University of Cologne, 50931 ...