Recognition of specific antigen through the B-cell receptor (BCR ... high-affinity antibodies and the provision of long-lasting memory responses to secondary encounters with the same antigen.

The BCR- and TCR-mediated immunological ... whereas the distinct lineage of FDCs may present antigens to activated B cells and evolving memory cells in the germinal centers. B cells may take ...

Three doses of COVID-19 mRNA vaccination induce long-lasting antibody and memory B-cell responses, according to a study of 113 health care workers in Catalonia who were followed for three years. The ...

When a booster was then given in the same location, the primed subcapsular sinus macrophages (SSMs)—already on alert— efficiently captured the antigen and activated the memory B cells to make ...

When a booster was given in the same location, these 'primed' macrophages—already on alert—efficiently captured the antigen and activated the memory B cells to make high-quality antibodies.

If you or a loved one has diffuse large B-cell lymphoma (DLBCL) that is no longer responding to treatment or came back after treatment, chimeric antigen receptor (CAR) T-cell therapy may be an option.

Memory B cells are essential for maintaining a long-term immune response: they rapidly proliferate upon antigen rencounter ... memory B cells recognising the receptor-binding domain (RBD) of ...