Imprint has raised $15 million to decode the body's immune memory for understanding chronic diseases, such as long-COVID and ...

An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according ...

If you or a loved one has diffuse large B-cell lymphoma (DLBCL) that is no longer responding to treatment or came back after treatment, chimeric antigen receptor (CAR) T-cell therapy may be an option.

When a booster was then given in the same location, the primed subcapsular sinus macrophages (SSMs)—already on alert— efficiently captured the antigen and activated the memory B cells to make ...

When a booster was given in the same location, these 'primed' macrophages—already on alert—efficiently captured the antigen and activated the memory B cells to make high-quality antibodies.

Nevertheless, it remains unclear which bacterial antigens should be targeted to trigger a potent complement response. Memory B-cells (mBCs) express membrane-bound antibodies as B-cell receptors ...

Antigen-presenting cells (APCs), such as dendritic cells and macrophages, are essential for initiating and regulation of anti-tumor T cell responses.

Lyell is advancing a pipeline of next-generation CAR T-cell product candidates. Its lead program, LYL314, is in Phase 1/2 ...

"By talking to the memory B cells, they can help direct them to mutate the receptor and make better antibodies." While there are no official guidelines on whether you should receive your vaccine ...

Presenting new clinical data from Phase 1/2 multi-center clinical trial of LYL314, a next-generation dual-targeting CD19/CD20 CAR T-cell product candidate for the treatment of relapsed and/or refracto ...