IL-17A-producing NKp44(−) group 3 innate lymphoid cells accumulate in Familial Adenomatous Polyposis duodenal tissue. Nature Communications , 2025; 16 (1) DOI: 10.1038/s41467-025-58907-y Cite ...

Familial adenomatous polyposis is an inherited condition that significantly increases the risk for colon cancer. The Food and Drug Administration (FDA) has granted Orphan Drug designation to TPST ...

Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer. At present, the only treatment ...

Indore (Madhya Pradesh): A special crackdown was launched on Thursday against unauthorised ambulance operations in the MY Hospital premises. As a result of the action, five ambulances operating ...

The trial evaluates the safety and efficacy of REC-4881 for treating familial adenomatous polyposis (FAP), a rare genetic condition with no FDA-approved therapies available. Preliminary results ...

Tempest Therapeutics, Inc. has announced that the FDA has granted Orphan Drug Designation to its dual receptor inhibitor TPST-1495 for treating Familial Adenomatous Polyposis (FAP), a rare genetic ...

The designation covers the use of Tempest's TPST-1495, an inhibitor of prostaglandin signaling, for the treatment of familial adenomatous polyposis, an inherited syndrome associated with the ...

Amvuttra (vutrisiran) Transthyretin-directed small interfering RNA therapeutic Treatment of the cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis in adults to reduce ...

A gut toxin that’s been linked to colorectal cancers for more than two decades may be contributing to the sharp rise of the disease in younger people, according to landmark research published ...