Absence of Progression As Assessed by Response Evaluation Criteria in Solid Tumors Predicts Survival in Advanced GI Stromal Tumors Treated With Imatinib Mesylate: The Intergroup EORTC-ISG-AGITG Phase ...

Biodexa Pharmaceuticals PLC announced that the European Commission has granted Orphan Drug Designation for its drug eRapa, aimed at treating familial adenomatous polyposis (FAP), a hereditary ...

Its lead candidates -- including REC-4881 for familial adenomatous polyposis and REC-7735 for breast cancer -- have demonstrated promising early results. The company's AI-first approach enables ...

IL-17A-producing NKp44(−) group 3 innate lymphoid cells accumulate in Familial Adenomatous Polyposis duodenal tissue. Nature Communications , 2025; 16 (1) DOI: 10.1038/s41467-025-58907-y Cite ...

Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer. At present, the only treatment ...

Familial adenomatous polyposis is an inherited condition that significantly increases the risk for colon cancer. The Food and Drug Administration (FDA) has granted Orphan Drug designation to TPST ...

The designation covers the use of Tempest's TPST-1495, an inhibitor of prostaglandin signaling, for the treatment of familial adenomatous polyposis, an inherited syndrome associated with the ...

Indore (Madhya Pradesh): The state government has announced a major investment of Rs 700 crore for the upgrade and redevelopment of Maharaja Yeshwantrao Hospital (MYH), the largest government-run ...

Colorectal cancer stands as the third leading cause of cancer-related deaths in US men and the fourth leading cause in US women, according to the American Cancer Society. This year, over 150,000 ...

The trial will focus on patients with Familial Adenomatous Polyposis (FAP), indicating the company is addressing urgent medical needs in a high-risk patient population. This initiative is ...

The planned Phase 2 study will evaluate the efficacy and safety of TPST-1495 in patients with Familial Adenomatous Polyposis (FAP) who have previously undergone colectomy. The primary efficacy ...