Panelists discuss how Janus kinase (JAK) inhibitors like pacritinib offer crucial treatment options for myelofibrosis patients with severe thrombocytopenia (platelet counts <50,000 ), highlighting its ...

Panelists discuss how survival data from the COMFORT trials support the use of ruxolitinib in myelofibrosis, especially in intermediate- to high-risk patients with significant symptom burden or ...

Like a creature from a science fiction movie, chronic lymphocytic leukemia (CLL) can be a shape-shifter. In a small number of ...

Long-term use of propylthiouracil (PTU) may precipitate antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) complicated by hemophagocytic activity, according to a case report ...

Symptoms include enlargement of the spleen (splenomegaly) and liver (hepatomegaly), bone pain or fractures, fatigue, and easy bruising. Type 2 (acute neuronopathic): This form is much rarer and ...

Extrahepatic portal hypertension is commonly caused by portal vein thrombosis (PVT). Clinical manifestations of this may include splenomegaly, varices and ascites. Rare complications such as splenic ...

But doctors at the health facility diagnosed him with Kala-azar, a common disease in the area with signs and symptoms of significant weight loss, persistent fever, progressive anaemia (pancytopenia), ...

IL6 transgene into mice gives rise to the abnormalities such as hyper-γ-globulinaemia, thrombocytosis, infiltration of inflammatory cells into the tissues, mesangial cell proliferation of the kidney ...

Clinical findings included lower limb neurological deficits, thrombocytopenia and splenomegaly. Further investigation revealed neuroinflammation on MRI, progressive cytopenias, raised inflammatory ...

If it becomes enlarged (a condition called splenomegaly), it may hold on to too many and prevent them from circulating in your bloodstream—causing a low platelet count. The treatment for ...