With Brainiac's resources and intelligence, Batman would be able to use his methodical thinking to likely defeat any planet in the universe with ease, which makes him one of the most dangerous ...
Then there’s the fact that Brainiac quite literally uses Batman/Flash DNA to make new enemies that you fight against in combat. All of this is DNA-based stuff, not just some mind-control ...
Perhaps the easiest string to follow and knot in a future Arkhamverse game is the aftermath of Metropolis’ Brainiac invasion, and if a sequel decided to focus entirely on Batman’s mythology ...