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Led by researchers at the University of Laval in Canada, the study found that mice with increased levels of cannabinoid ...
Learn all about THCP’s effects and benefits and where to buy this naturally occurring cannabinoid, which is more potent than ...
A study published in Nature Neuroscience suggests that the cannabinoid receptor type 1 (CB1) could play a role in regulating stress responses by maintaining vascular integrity in the brain. The ...
Dr. Chris Twitty, Chief Scientific Officer of Skye, said, “These data demonstrate for the first time how nimacimab’s allosteric binding to the CB1 receptor is differentiated from the small molecules ...
“At lower doses, it acts as a CB 1 antagonist, prevents THC from binding to the CB 1 receptor, reduces psycho-activity, and increases appetite control by potentially increasing insulin ...
Agonists of the type 1 cannabinoid receptor (CB1) show promise as alternative analgesics but are still limited by side effects and tolerance. Reporting in Nature, Rangari et al. apply computation ...
“This new preclinical study highlights that a truly peripherally-restricted CB1 inhibitor—nimacimab—effectively drives weight loss in a DIO model. Nimacimab compared favorably to and ...