In this novel process, drug molecules are designed to better engage with CD36, a protein receptor found on the surface of many cells. By optimizing chemical interactions with CD36, the team was ...

The new method works by taking advantage of a protein called CD36 that helps pull substances into cells. By designing drugs to use this CD36 pathway, researchers delivered 7.7 to 22.3 times more ...

This antibody, PLT012, binds and blocks the activity of CD36, a transporter of lipids that is expressed by immune cells in fat-enriched tumor microenvironments (TMEs). As Ho, Yu and colleagues ...

Details are provided in a new Cell paper titled, “CD36-mediated endocytosis of proteolysis-targeting chimeras.” PROTACs are small molecules that use the ubiquitin-proteasome system to remove ...