We identify genomic regions with significantly different chromatin accessibility in adult SPGs that are marked by histone modifications associated with enhancers and promoters. Some of the regions ...

School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China ...

This valuable research advance builds upon previous studies to convincingly show that the centromere-histone core contributes to force transduction through the kinetochore. The centromere mainly ...

The South Dakota Game, Fish and Parks (GFP) held their April Commission meeting at the Matthews Training Center in Pierre. The Commission had several proposals and finalizations for upcoming seasons ...

Figure 1. An overview of epigenetic mechanisms. The basic unit of chromatin is the nucleosome. Two molecules of H2A, H2B, H3, and H4 form a histone octamer, and DNA molecules are coiled around the ...

to image indiviual histone or histone complexes on different channels. Results: Single histones (H2A, macroH2A1.1, macroH2A1.2 H2B, H3, H4 and histone H3 bearing the H3K27M mutation), and histone ...

Here we present CHAS (cell type-specific histone acetylation score), an R package for the cell deconvolution of bulk brain H3K27ac profiles. CHAS is split into two independent algorithms. In the first ...

The fundamental unit of chromatin is the nucleosome particle, consisting of core histone proteins (H2A, H2B, H3, and H4) around which the DNA is wrapped. Chromatin is often broadly divided into two ...