A Maine woman is dead, and a Florida man was injured, in a two-vehicle crash on Interstate 81 in Frederick County on Monday.

An Ivanhoe woman is dead after she was ejected from her vehicle in an accident Friday night on Interstate 81 northbound in ...

PennDOT is advising motorists of traffic restrictions on Interstate 81 north and south in Lackawanna County.According to ...

As the weather begins to warm, construction kicks into full gear — with a few I-81 closures coming up that you should look ...

Six vehicles were involved in an accident early on the morning of May 13 on Interstate 81 in Berkeley County, West Virginia.

More work is set in motion for the Interstate 81 Viaduct Project. The New York State Department of Transportation wants to ...

Virginia State Police are investigating a fatal single-vehicle crash that occurred late Friday night on Interstate 81 ...

The $18 million flyover ramp passes over the mainline of I-81 and carries traffic from future Business Loop 81 Northbound to ...

New York State has awarded Salt City Constructors the fifth and final contract of the initial phase of the Interstate 81 ...

This story has been updated to include information from Tennessee Highway Patrol (THP). GREENE COUNTY, Tenn. (WJHL) — Cleanup ...

PennDOT has announced lane restrictions on Interstate 81 in both directions in Lackawanna County, lasting until Friday. Lane ...

Lane restrictions for line painting will be in place on Interstate 81 northbound and southbound in Lackawanna County, the state Department of Transportation announced Monday. Drivers ...